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?Duramune Max 5 is 5-way Modified live. For protection against canine distemper, adenovirus type 2 (and hepatitis), parainfluenza and parvovirus. For dogs 6 weeks of age or older. Give 1 ml SQ. Beginning at or about 6 weeks of age, give every 2 to 3 weeks until 12 weeks of age. If primary vaccination is given after 12 weeks of age, give 2 doses, 2-3 weeks apart. Annual revaccination with a single dose is recommended. Requires mixing. Order syringes separately.